The Biophysical Instrumentation Facility (BIF) @ MIT houses instrumentation for aiding in the elucidation of macromolecular structures and interactions.

The BIF is located in the MIT Biology Building (68-470: https://whereis.mit.edu/) on Ames Street near Kendall Square. The BIF is used by MIT researchers in Chemistry, Biology, Biological Engineering, and Chemical Engineering and is available to all members of the MIT community and beyond.

The BIF maintains A JASCO Circular Dichroism Spectrometer, a Prometheus PANTA nanoDSF with parallel DLS, a Sartorius Octet R8 Biolayer Interferometry system, a Refeyn-One Mass Photometer, a MicroCal Isothermal Titration Calorimeter, a Wyatt Dynamic Light Scattering instrument, and an Agilent HPLC with SEC-MALS system.

Dr. Ky Lowenhaupt, who manages the BIF, is available to train new users and advise those considering the potential application of the instruments in the facility.

ONLINE SIGN-UP FOR TRAINED MIT USERS IS ACTIVE

THESE ARE THE INSTRUMENTS - SEE LINKS IN HEADER FOR ALL YOU NEED TO KNOW!

For all inquiries, please contact Dr. Ky Lowenhaupt - bif@mit.edu

The BIF is a BL1 facility

We request that you do not bring hazardous or toxic chemicals into the BIF, as all of the instruments are on the open benchtops. Thank you!

Prof. Barbara Imperiali established the BIF through NIH, NSF, and MIT funding.